Showing posts with label Health. Show all posts
Showing posts with label Health. Show all posts

Senate’s “fiscal cliff” bill packed with sweeteners






WASHINGTON (Reuters) – The Senate packed an eclectic mix of handouts and takebacks into its last-minute deal to avoid the “fiscal cliff,” including a measure to repeal part of President Barack Obama‘s signature healthcare overhaul and a string of special interest tax breaks.


At the center of the 157-page bill adopted early Tuesday are provisions to raise taxes on the wealthiest households and to make permanent Bush-era tax cuts for the middle class. The bill now goes to the Republican-controlled House of Representatives.






But senators also extended higher rum excise taxes to Puerto Rico and the U.S. Virgin Islands and provided tax breaks to a wide range of other groups and interests, including motorsports entertainment complexes and mine rescue teams.


Among the other sweeteners:


* special expensing rules for certain film and TV productions


* tax-exempt financing for New York Liberty Zone, an area around the site of the World Trade Center.


* extension of American Samoa economic development credit


Congressional lawmakers often insert pet projects and other unrelated provisions into major “must do” bills in the last days of a legislative session, when it is more likely that quick passage will occur.


Green energy was another big winner in the bill. Roughly a dozen provisions would extend credits and incentives for plug-in electric vehicles, energy-efficient appliances, biodiesel and renewable diesel, and other alternative energy initiatives.


The legislation also would kill the part of Obama’s 2010 Affordable Care Act designed to let millions of elderly and disabled people get help at home rather than be placed in institutional care, which tends to be more expensive.


Democrats acknowledge that the insurance initiative known as the Community Living Assistance Services and Support program, or CLASS, is financially flawed but they had argued it should be fixed rather than ended.


The House voted to repeal that provision 11 months ago.


Also tucked in the bill, known as the American Taxpayer Relief Act of 2012, are measures to avert the so-called “dairy cliff” – a steep increase in milk prices that would otherwise take place this year.


The measures would extend farm subsidy programs and prevent dairy subsidies from reverting to 1949 levels, which would have meant retail milk prices could have doubled to about $ 7 per gallon.


One thing lawmakers did not slide into the legislation: a raise for themselves. The Senate bill says members of Congress will get no cost-of-living adjustment in their pay for fiscal year 2013.


(Reporting by Jim Wolf; Editing by Karey Wutkowski and Paul Simao)


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Texas judge OKs ban on Planned Parenthood funding






AUSTIN, Texas (AP) — Texas can cut off funding to Planned Parenthood‘s family planning programs for poor women, a state judge ruled Monday, requiring thousands to find new state-approved doctors for their annual exams, cancer screenings and birth control.


Judge Gary Harger said that Texas may exclude otherwise qualified doctors and clinics from receiving state funding if they advocate for abortion rights.






Texas has long banned the use of state funds for abortion, but had continued to reimburse Planned Parenthood clinics for providing basic health care to poor women through the state’s Women’s Health Program. The program provides preventive care to 110,000 poor women a year, and Planned Parenthood clinics were treating 48,000 of them.


Planned Parenthood’s lawsuit to stop the rule will still go forward, but the judge decided Monday that the ban may go into effect for now. In seeking a temporary restraining order, Planned Parenthood wanted its patients to be able to see their current doctors until a final decision was made.


“We are pleased the court rejected Planned Parenthood’s latest attempt to skirt state law,” attorney general spokeswoman Lauren Bean said. “The Texas Attorney General’s office will continue to defend the Texas Legislature‘s decision to prohibit abortion providers and their affiliates from receiving taxpayer dollars through the Women’s Health Program.”


Ken Lambrecht, president and CEO of Planned Parenthood of Greater Texas, said he brought the lawsuit on behalf of poor women who depend on its clinics.


“It is shocking that once again Texas officials are letting politics jeopardize health care access for women,” Lambrecht said. “Our doors remain open today and always to Texas women in need. We only wish Texas politicians shared this commitment to Texas women, their health, and their well-being.”


Planned Parenthood has brought three lawsuits over Texas’ so-called “affiliate rule,” claiming it violates the constitutional rights of doctors and patients while also contradicting existing state law.


Republican lawmakers who passed the affiliate rule last year have argued that Texas is an anti-abortion state, and therefore should cut off funds to groups that support abortion rights. Gov. Rick Perry, who vehemently opposes abortion, has pledged to do everything legally possible to shut down Planned Parenthood in Texas and welcomed the court’s ruling.


“Today’s ruling finally clears the way for thousands of low-income Texas women to access much-needed care, while at the same time respecting the values and laws of our state,” Perry said. “I applaud all those who stand ready to help these women live healthy lives without sending taxpayer money to abortion providers and their affiliates.”


The Texas Health and Human Services Commission has spent the last nine months preparing to implement the affiliate rule. But federal officials warned it violated the Social Security Act and cut off federal funds for the Women’s Health Program, prompting the commission to start a new program using only state money.


State officials have also scrambled to sign up new doctors and clinics to replace Planned Parenthood. Women who previously went to Planned Parenthood clinics will now have to use the agency’s web site to find a new state-approved doctor. HHSC officials acknowledged Monday they are unsure whether the new doctors can pick up Planned Parenthood’s caseload in all parts of the state.


Any capacity issues will become clear in the next few weeks as women try to make appointments with new clinics and doctors, with problems anticipated in South Texas and other impoverished areas. Texas already suffers from a shortage of primary care physicians willing to take on new patients who rely on state-funded health care.


Linda Edwards Gockel, a spokesman for the Texas Health and Human Services Commission, said Monday that the new state program will launch as planned on Tuesday.


“We have more than 3,500 doctors, clinics and other providers in the program and will be able to continue to provide women with family planning services while fully complying with state law,” she said. “We welcome Planned Parenthood’s help in referring patients to providers in the new program.”


Democratic lawmakers continued to question whether women will have to wait longer for appointments and services.


“I vehemently disagree with the state’s efforts to blacklist a qualified provider and, thereby, interfere with a woman’s right to choose her own provider,” said state Rep. Donna Howard, D-Austin. “I will be submitting a letter to the Texas Health and Human Services Commission, requesting a list of approved providers to gauge the outreach of the new program, and ensure that all qualified women throughout the state have access to its services.”


Another hearing is scheduled with a different judge for Jan. 11, where Planned Parenthood will again ask for an injunction to receive state funding.


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New Year’s Resolutions For Better Health






New Year’s resolutions are typically so singular, self-focused and private. How about making a resolution or two this year that has benefits beyond yourself? Here are some suggestions with lots of links to get you started.


You can help stop the spread of disease. Resolve to get up-to-date on your vaccines. While children have a full slate of vaccines, many adults don’t realize they have regular immunization obligations, too. Getting flu, pertussis, human papillomavirus and other vaccines can protect you and help stop the spread of diseases that harm others. Here’s a great guide to adult immunizations from the federal government. If the cost of vaccines is an issue, check into free or low-cost immunizations through your county’s public health department. Here’s a guide to finding your local office. Volunteer with an organization that needs your help. A group called Catchafire matches professionals who wish to volunteer their skills to organizations that need the help — including many important health organizations. The idea is to give great organizations access to top talent while respecting the professionals’ schedules and making their volunteer work meaningful. Here’s the link. Influence a healthier food climate. Americans spend about half of their food budgets eating out. So we had better demand thorough nutritional information about what we’re getting. Under healthcare reform, many restaurant chains will soon carry nutritional information. But the law has loopholes. If you don’t see the information you’re looking for on salt, fat, calories or other nutrients, ask the restaurant’s manager where you can find it. Nutritional information should be easy to access. Until it is, speak up and ask for it. Do your part to keep down healthcare costs. The Affordable Care Act will bring many consumers into the insurance healthcare system for the first time. But that doesn’t mean we can ignore the cost of care. Rising healthcare costs remain a huge issue that could drag down the economy and bedevil some reform efforts. You can help by being a wise healthcare consumer. Read your insurance policy and know what it does and doesn’t cover. Take advantage of free preventive care services and screening tests under the ACA. Shop around for prescriptions to find the cheapest prices. Ask your doctor for generic equivalents. Finally, use your health savings account if your employer offers one. These accounts provide incentives for using your money wisely, shopping around to find the best healthcare prices and weighing the costs and benefits of certain drugs, tests or procedures.  Here’s a guide to understanding how HSAs work. Be responsible about the prescription drugs you store at home. You can reduce your own risk of addiction and lower the risk for others, too, if you are careful about medications kept in your home. This year marked a turning point in the nation’s epidemic of prescription-drug abuse and addiction.  Admissions to addiction treatment centers for use of narcotic painkillers rose 569 percent in the past decade, according to the federal government. More people now die from drug overdoses than from traffic accidents. More than six million Americans abuse prescription drugs, and more than 70 percent of addicts get their drugs through family or friends or by raiding a home medicine cabinet. Dispose of unused medications. The Drug Enforcement Agency operates a National Prescription Drug Take-Back Day a few times a year (the next one is in April), that makes it easy to dispose of dangerous substance.  Go through your home today and collect unused medications. You can take them to a pharmacy for disposal or even flush them down the toilet. Some drugs carry disposal instructions on the label. Here’s information on how to dispose of prescription medications. Be a safe driver. One of the biggest safety issues on the nation’s roads these days is driver distraction. A large share of the distractions come from talking on a hand-held cell phone or text messaging while driving. You’re 23 times more likely to crash if you text while driving. Most states now prohibit texting while driving, but there are still many people who do it while knowing it’s unsafe. Break yourself of this terrible habit. The federal government has a website that provides people with information and tools to discourage distracted driving. Included in this package is a simple pledge sheet you can print out, sign and post on your refrigerator door or bathroom to help you make the commitment. There are a couple of other things you can do, too. Speak out if the driver you’re riding with is distracted. Encourage family and friends to drive phone-free. Run a race for the greater good. Who doesn’t love a good 5K walk or run? You benefit from the exercise and, if you choose a charity race, others reap rewards, too. There are thousands of charity races each year. Pick one and invite your friends to participate with you. Here’s a website to help you find a race.  Apply for a grant. There’s money out there for doing good. Saucony’s Run for Good Foundation aims at preventing child obesity by promoting running as part of a healthy lifestyle for kids. The foundation issues grant money to organizations that want to organize a kids’ running group. You can find information on how to apply at the foundation website. Sign a petition. Concerned about flame retardants in consumer products? Gun safety? Funding for research to fight a particular disease? There’s probably a petition for that. It’s an easy way to make your voice heard. Both change.org and thepetitionsite.com are good places to look to find a petition close to your heart.






Question: What resolutions can you make to help others? Tell us what you think in the comments.



Shari Roan is an award-winning health writer based in Southern California. She is the author of three books on health and science subjects.


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FDA approves Bristol Myers, Pfizer’s anti-clotting drug Eliquis






(Reuters) – U.S. health regulators approved clot prevention drug Eliquis, developed by Bristol Myers-Squibb Co and Pfizer Inc, for treatment in patients with atrial fibrillation, or irregular heartbeats.


The drug, also known as apixaban, was approved by European health regulators last month.






Eliquis belongs to a new class of medicines designed to replace decades-old warfarin for preventing blood clots in heart patients, or after a hip- or knee-replacement surgery.


Eliquis would compete against approved blood clot preventers such as Xarelto from Johnson & Johnson and Bayer, and Pradaxa from Boehringer Ingelheim.


Treating atrial fibrillation, which greatly raises the risk of strokes, is considered by far the largest and most important use for these new drugs.


The oral tablet Eliquis, like Xarelto, works by inhibiting a protein called Factor Xa that plays a critical role in blood clotting. Pradaxa has a slightly different mechanism of action.


However, Eliquis should not be taken by patients with prosthetic heart valves or those with atrial fibrillation caused by a heart valve problem, the U.S. Food and Drug Administration said in a statement.


About 5.8 million people in the United States suffer from atrial fibrillation, the most common form of heart arrhythmia, or irregular heartbeat.


Bristol-Myers shares were up 2 percent at $ 32.48 and Pfizer shares were up 10 cents at $ 24.99 in extended trading.


(Reporting by Prateek Kumar; Editing by Sreejiraj Eluvangal)


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Surival Rates Similar for Two Types of Abdominal Aneurysm Repairs






Less-invasive surgery isn’t necessarily better than an open procedure to repair a potentially fatal abdominal aortic aneurysm. That’s the conclusion of researchers at the Johns Hopkins University School of Medicine, who found similar survival rates for both types of procedures.


The medical community was enthusiastic about a new, less-invasive procedure assumed to be safer and better than traditional open surgery, according to Medical News Today. The researchers followed patients for up to nine years. Surprisingly, they found that after four years, survival rates for the two types of surgery were very similar.






An aneurysm is a bulge resembling a balloon in an artery. When the artery’s wall has been weakened by genetic issues, trauma, or certain medical problems, the pressure of blood against it can cause an aneurysm. Aneurysms in the aorta claim the lives of around 13,000 Americans a year, says the National Heart Lung and Blood Institute. Most deaths occur after the rupture of an aneurysm or a split in the aorta’s wall.


An abdominal aortic aneurysm occurs when the aorta — the body’s largest blood vessel — balloons in the abdomen due to pressure on the wall. If it ruptures, massive bleeding can be quickly fatal. This type of aneurysm ranks 14th among leading causes of death for Americans between 60 and 85.


Treatment depends on an aneurysm’s size and location. The traditional surgery for an abdominal aortic aneurysm utilizes a large, open cut. The more recent type of repair is an endovascular embolization, in which the surgeon uses a stent to prop open the blood vessel or reinforce its wall, according to PubMed Health.


While the survival rate was higher after two years in patients in the Hopkins study who had undergone endovascular repair, by the four-year mark, rates were nearly the same. Among elderly patients considered bad risks for an open surgery, individuals didn’t fare better with the newer technique. The team found no increased survival in patients at least 70 years old who had undergone the less-invasive procedure. Any benefits occurred in younger individuals.


Study leader Julie A. Freischlag, M.D., says the results raise an issue over who should undergo aneurysm repair. Even when older patients underwent repairs, their lives weren’t prolonged. She says the issue is whether they should have either procedure, since they’re already dying of diseases associated with old age.


My father lived, largely symptom-free, for years with an abdominal aortic aneurysm . Citing a weak heart, surgeons declined to repair it. When he experienced sudden pain, my mother took him to the emergency room. He survived an open repair procedure but died after 16 days in intensive care of an infection at the surgical site. Although he was 71, we wonder if an endovascular embolization would have provided a different outcome, at least for four years after surgery.


Vonda J. Sines has published thousands of print and online health and medical articles. She specializes in diseases and other conditions that affect the quality of life.


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Mayo Scientists Link Enzyme to Aggressive Prostate Cancer






Researchers from the Mayo Clinic have directly linked an enzyme to aggressive prostate cancer. They’ve also developed a compound that restricts the ability of the molecule to fuel metastases of this type of cancer.


The team from Mayo’s Florida campus identified the first direct relationship between the enzyme known as PRSS3 to prostate cancer, according to Medical News Today. They published their results in Molecular Cancer Research.






The National Cancer Institute estimated that close to a quarter of a million men would be diagnosed with prostate cancer in 2012, and around 28,000 of them wouldn’t survive.


For years, medical professionals have relied on two types of screening for this disease: a digital rectal exam and the prostate specific antigen (PSA) test. However, the Mayo Clinic says using the PSA test is sometimes controversial, since it can provide false indicators and since there is no proof that it actually saves lives.


PRSS3, a protease, digests other molecules. The Mayo researchers concluded that activity associated with the enzyme alters the environment surrounding prostate cancer cells. They suspect that PRSS3 frees the cells from surrounding tissue, allowing them to become invasive and to spread cancer.


They haven’t concluded that the enzyme is the only issue linked to aggressive prostate cancer, however. Instead, they suspect that PRSS3 might power a potentially lethal form of this cancer.


The researchers examined databases available to the public that contained information from clinical studies. After finding a link between early breast cancer and protease in earlier work, they sought to discover whether any other type of cancer expressed protease and at which stages of the disease.


They found a dramatic relationship between increases in PRSS3 expression and progression of aggressive prostate cancer. The scientists determined that protease expression played a critical role in prostate cancer metastasis in mice models and found a site for an inhibiting agent to shut down the expression. In mice in which PRSS3 was “shut off,” the malignancy did not spread.


One outcome of the study is the possibility of testing prostate cancer patients for the molecule. Doctors could better determine patients at highest risk for an aggressive form of the disease. While the inhibitor utilized cannot be directly developed into a useful drug, it could provide a template for creating one.


My husband is among those who could eventually profit from this study. After two successive PSA tests with numbers that suddenly skyrocketed, he underwent painful biopsies that showed nothing amiss. Although his PSA numbers bounce, his urologist insists that he keep repeating the test.


With a family history of aggressive prostate cancer, my husband finds it hard to argue. Should he nix more PSA tests and eventually develop the illness, the link between the enzyme and prostate cancer provides some hope of a positive outcome.


Vonda J. Sines has published thousands of print and online health and medical articles. She specializes in diseases and other conditions that affect the quality of life.


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Link between pot, psychosis goes both ways in kids






NEW YORK (Reuters Health) – Marijuana (cannabis) use may be linked to the development of psychotic symptoms in teens – but the reverse could also be true: psychosis in adolescents may be linked to later pot use, according to a new Dutch study.


“We have focused mainly on temporal order; is it the chicken or the egg? As the study shows, it is a bidirectional relationship,” wrote the study’s lead author Merel Griffith-Lendering, a doctoral candidate at Leiden University in The Netherlands, in an email to Reuters Health.






Previous research established links between marijuana and psychosis, but scientists questioned whether pot use increased the risk of mental illness, or whether people were using pot to ease their psychotic symptoms, such as hallucinations and delusions.


“What is interesting in this study is that both processes are going on at the same time,” said Dr. Gregory Seeger, medical director for addiction services at Rochester General Hospital in upstate New York.


He told Reuters Health that researchers have been especially concerned about what tetrahydrocannabinol (THC), the active property in pot, could do to a teenager’s growing brain.


“That’s a very vulnerable period of time for brain development,” and individuals with a family history of schizophrenia and psychosis seem to be more sensitive to the toxic effects of THC, he said.


A 2010 study of 3,800 Australian teenagers found that those who used marijuana were twice as likely to develop psychosis compared to teens who never smoked pot (see Reuters Health article of March 1, 2010 here:).


But that study also found that those who suffered from hallucinations and delusions when they were younger were also more likely to use pot early on.


CHICKEN v. EGG


For the new study, published in the journal Addiction, the researchers wanted to see which came first: pot or psychosis.


Griffith-Lendering and her colleagues used information on 2,120 Dutch teenagers, who were surveyed about their pot use when they were about 14, 16 and 19 years old.


The teens also took psychosis vulnerability tests that asked – among other things – about their ability to concentrate, their feelings of loneliness and whether they see things other people don’t.


Overall, the researchers found 940 teens, or about 44 percent, reported smoking pot, and there was a bidirectional link between pot use and psychosis.


For example, using pot at 16 years old was linked to psychotic symptoms three years later, and psychotic symptoms at age 16 were linked to pot use at age 19.


This was true even when the researchers accounted for mental illness in the kids’ families, alcohol use and tobacco use.


Griffith-Lendering said she could not say how much more likely young pot users were to exhibit psychotic symptoms later on.


Also, the new study cannot prove one causes the other. Genetics may also explain the link between pot use and psychosis, said Griffith-Lendering.


“We can say for some people that cannabis comes first and psychosis comes second, but for some people they have some (undiagnosed) psychosis (and) perhaps cannabis makes them feel better,” said Dr. Marta Di Forti, of King’s College, London, who was not involved with the new research.


Di Forti, who has studied the link between pot and psychosis, told Reuters Health she considers pot a risk factor for psychosis – not a cause.


Seeger, who was also not involved with the new study, said that there needs to be more public awareness of the connection.


“I think the marijuana is not a harmless substance. Especially for teenagers, there should be more of a public health message out there that marijuana has a public health risk,” he said.


Griffith-Lendering agrees.


“Given the severity and impact of psychotic disorders, prevention programs should take this information into consideration,” she said.


SOURCE: http://bit.ly/Rr63N8 Addiction, online December 7, 2012.


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‘Dystextia’: Gibberish texts sound stroke alarm






NEW YORK (Reuters Health) – Imagine you were a devoted husband, waiting to hear from your wife about her due date after a visit to the obstetrician, and you saw these on your phone:


“every where thinging days nighing”






“Some is where!”


That’s what happened last December to a Boston-area man, who knew that autocorrect – known for its bizarre replacements – was turned off on his 11-week-pregnant wife’s phone.


You’d probably be tempted to make sure your wife, 25, got to the emergency room. When she did, doctors noted several signs of a stroke, including disorientation, inability to use her right arm and leg properly and some difficulty speaking.


A magnetic resonance imaging scan – MRI – revealed that part of the woman’s brain wasn’t getting enough blood, clinching the diagnosis. Fortunately, her symptoms went away quickly, and the rest of the pregnancy went just fine after she went home from the hospital on low-dose blood thinners.


The case, say three doctors from Boston’s Harvard Medical School who reported it online today in the Archives of Neurology, suggests that “the growing digital record will likely become an increasingly important means of identifying neurologic disease, particularly in patient populations that rely more heavily on written rather than spoken communication.”


The authors describe the phenomenon as “dystextia,” which is the word used by other doctors in an earlier case involving a migraine, and symptoms of a stroke diagnosed for other reasons.


“In her case, the first evidence of language difficulties came from her unintelligible texts,” one of the report’s authors, Dr. Joshua Klein, told Reuters Health by email.


Strokes are rare in women aged 15 to 34, with about 11,000 per year, according to data from the U.S. Centers for Disease Control and Prevention published last year.


Dr. Sean Savitz, who directs the stroke program at the University of Texas Health Science Center in Houston, said he has seen a few patients who sent emails suggesting they were having difficulty with language, a condition known as aphasia.


Such clues usually come with other information however. In this case, for example, the patient’s obstetrician’s office later remembered that she had trouble filling out a form. And they might have caught the language difficulty earlier had the woman not had a weak voice, thanks to a recent upper respiratory infection.


“So, this case report per se does not indicate to me if dystextia is going to be more common to pick up strokes,” Savitz told Reuters Health by email, “but I do think it will be a valuable addition to the collection of information that neurologists should obtain when taking a history.”


“The main stroke warning signs with respect to texting would be unintelligible language output, or problems reading or comprehending texts,” said Klein. “Many smartphones have an ‘autocorrect’ function which can introduce erroneous word substitutions, giving the impression of a language disorder.”


Autocorrect, said Savitz, a professor of neurology, can confuse matters – even for doctors.


“I have often joked with my colleagues when using the dictation of the smartphone, that it gives me an aphasia,” he said. “Potential for lots of false positives!”


SOURCE: Archives of Neurology, online December 24, 2012.


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No new vote in Venezuela if Chavez sworn in late: official






CARACAS (Reuters) – Venezuela will not call fresh elections if Hugo Chavez‘s cancer prevents him from taking office by January 10, the head of Congress said on Saturday, despite a constitutional mandate that the swearing-in take place on that date.


Chavez is recovering in Cuba from a six-hour cancer operation that followed his October re-election. The socialist leader has not been heard from for nearly two weeks, raising doubts as to whether he will be fit to continue governing.






Opposition leaders may pounce on the issue of the swearing-in date to demand that authorities call fresh elections because of Chavez’s apparently critical state of health due to an undisclosed type of cancer in the pelvic region.


A constitutional dispute over succession could lead to a messy transition toward a post-Chavez era in the South American nation with the world’s largest oil reserves.


“Since Chavez might not be here in on January 10, (the opposition) hopes the National Assembly will call elections within 30 days. They’re wrong. Dead wrong,” said Diosdado Cabello, the National Assembly’s president and one of Chavez’s closest allies, during a ceremony to swear in a recently elected governor.


“That’s not going to happen because our president is named Hugo Chavez, he was reelected and is in the hearts of all Venezuelans.”


He suggested Chavez may need more time to recover from his surgery. Officials in recent weeks have recognized his condition was serious, and the garrulous leader’s unusual silence has built up alarm even among supporters.


The constitution says “the elected candidate will assume the Presidency of the Republic on January 10th of the first year of their constitutional term, via swearing-in by the National Assembly.”


It says new elections are to be called if the National Assembly determines a “complete absence” of the president because of death, physical or mental impairment or abandoning the job.


The opposition believes it would have a better shot against Chavez’s anointed successor, Vice President Nicolas Maduro, than against the charismatic former soldier who for 14 years has been nearly invincible at the ballot box.


Chavez allies want to avoid a public debate over the president’s health because his cancer has been treated as a state secret. His treatment in communist Cuba has helped keep his condition under wraps, and the Venezuelan government has given only terse and cryptic statements about his post-operation recovery.


Constitutional lawyer Jose Vice Harold said he expects the Supreme Court, which is controlled by Chavez allies, will rule that Chavez may extend his existing term without having to be sworn in with the expectation that he will eventually recover.


“What they are doing is taking the debate over succession from the National Assembly, which is where it belongs, and moving it to the Supreme Court where behind closed doors they can decide the next steps are,” said Harold, a Chavez critic and constitutional law professor as the Universidad Catholic Andres Bellow.


Chavez has vastly expanded presidential powers and built a near-cult following among millions of poor Venezuelans, who love his feisty language and oil-financed social welfare projects.


Opposition leaders are smarting from this month’s governors elections in which Chavez allies won 20 of 23 states. They are trying to keep attention focused on day-to-day problems from rampant crime to power outages.


(Reporting by Brian Ellsworth; Editing by Paul Simao)


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Mother loses UK legal fight to stop son’s cancer radiotherapy






LONDON (Reuters) – A mother in Britain, who was so desperate to stop her cancer-stricken son having to undergo conventional medical treatment that she went into hiding with him, lost a court battle on Friday to prevent him receiving radiotherapy.


The case of Sally Roberts, 37, a New Zealander living in Brighton, southern England, and the plight of her seven-year-old son has made headlines in Britain.






Roberts wants to try alternative treatments first, including immunotherapy and photodynamic therapy for her son Neon. She has been told the boy needs treatment fast but fears the side-effects of conventional medicine.


Doctors treating the boy had warned that without radiotherapy he could die within three months


Judge David Bodey told the High Court in London the life-saving radiotherapy treatment could start against the mother’s wishes, the Press Association reported.


“The mother has been through a terrible time. This sort of thing is every parent’s nightmare,” the judge said.


“But I am worried that her judgment has gone awry on the question of the seriousness of the threat which Neon faces.”


The story of the sick blue-eyed blonde boy came to public attention earlier this month when Roberts prompted a nationwide police hunt by going into hiding with Neon for four days to stop him from undergoing the treatment.


The mother’s relentless battle in court also cast a light on the dilemmas parents can face when dealing with the illness of a loved one, considering the short-term and long-term risks of a treatment and handling conflicting medical information available at the click of a mouse.


Roberts said in court she had researched on the Internet her son’s condition – a fast-growing, high-grade brain tumor called medulloblastoma – and sought advice from specialists around the world because she did not trust British experts.


She feared radiotherapy would stunt the boy’s growth, reduce his IQ, damage his thyroid and potentially leave him infertile.


Earlier this week, a judge ruled that Neon could undergo emergency surgery to remove a tumor which had resisted an initial operation in October, despite opposition from his mother, who found he appeared to be recovering after what she said was a “heartbreaking” stay in hospital.


“EXPERIMENTAL AND UNPROVEN”


Surgeons said Neon’s operation on Wednesday had been successful but that radiotherapy was needed to ensure no residual tumor was left behind.


Neon’s father Ben, who lives in London and is separated from Roberts, has sided with his son’s doctors.


But his wife suggested exploring several alternative treatments, including immunotherapy, which mainly consists of stimulating the body’s immune system to fight cancerous cells, and photodynamic therapy, which uses a photosensitizing agent and a source of light to kill malignant cells.


The hospital treating Neon slammed “experimental and unproven” methods which entered “unchartered territory”. The hospital, which cannot be named, also questioned the credentials of some of the private specialists contacted by Roberts’s team.


The court heard that at least one of these could not even correctly spell medulloblastoma.


Radiotherapy is used to prevent cancer from spreading or striking back after surgery but it can damage nerve tissue and healthy brain cells.


Long-term side effects tend to be more common in children, whose nervous systems are still developing.


(Reporting by Natalie Huet; Editing by Sophie Hares)


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St. Clare Commons Announces Partnerships to Improve Senior Care in Northwest Ohio






St. Clare Commons, a Franciscan Living Community, has partnered with the Toledo Catholic Diocese, Blessed John XXIII Parish, St. Rose Parish, the Alzheimer’s Association, Wright State University’s Nursing Institute and others to couple science together with caring to improve senior care in Northwest Ohio.


Perrysburg, OH (PRWEB) December 20, 2012






The Sisters of St. Francis with Sylvania Franciscan Health and Franciscan Living Communities have chosen the Toledo Catholic Diocese, Blessed John XXIII Community, St. Rose Parish as partners in advocacy, education and ministry to seniors.


Other important healthcare partnerships are in the works that will soon be released. The Alzheimer’s Association of Northwest Ohio is among the first working relationships to provide education and resources to residents, families, staff and the greater community. St. Clare Commons has become an Alzheimer’s Early Detection Alliance member to help bring awareness and resources to those who have been affected by dementia.


Another leader in dementia care, Dr. Govind Bharwani, Ph.D., Director of Nursing Ergonomics & Alzheimer’s Care (Nursing Institute) and Co-Director of Ergonomics (College of Engineering) at Wright State University, has been instrumental in the very design of St. Clare Commons. Earlier this year, Long Term Living Magazine named Dr. Bharwani a “Leader of Tomorrow.”


What is an engineer doing in dementia healthcare? Another Franciscan Living Community, St. Leonard Franciscan Living Community sought Dr. Bharwani out to reduce caregiver injuries. After demonstrating great success in reducing injuries for direct care nurses and nursing assistants, the team at St. Leonard asked him to evaluate the campus’s dementia and Alzheimer’s space to reduce resident falls and injuries.


Dr. Bharwani took that challenge and created Behavior-Based Ergonomics Therapy (BBET) with St. Leonard in 2010 and has since proven overwhelmingly effective. Research has shown a 35% reduction in falls and 55% drop in use of PRN (emergency) medications. There was also a more than 50% jump in improved mood – and 60% fewer uses of certain anti-psychotic medications for behavior management.


With a lot of preparation, ergonomically designed features and proper training in use of space and abilities, residents feel better and even those who would normally withdraw are more engaged. Working with the many devices and systems as instructed by Dr. Bharwani, the team feels more at ease, residents feel less stressed. Everybody wins.


Dr. Bharwani has been recognized nationally and several Ohio communities have implemented his program to improve patient care. The team at St. Clare Commons is excited to bring his methods and tools to Northwest Ohio.


Future community education will be offered through St. Rose Parish, Blessed John XXIII and other local venues. St. Clare Commons, under construction, and expected to open in the summer of 2013, has been designed with education in mind with several meeting spaces.


In addition to meeting spaces, the 135,000 square-foot first phase building located on Five Point Road just east of State Route 25 in Perrysburg, Ohio, one mile south of Levis Commons, will include 60 private skilled nursing suites, 56 assisted living apartments and 36 studio apartments dedicated to specialized memory care.


A well-appointed chapel, state-of-the-art therapy lab, fountains, ponds, two rooftop terraces, a piano lounge, community rooms, a coffee shop, and many connections to Blessed John XXIII round out the world class amenities. Future phases include independent senior apartments, duplexes, ranch homes, a club house with a restaurant and pool, and much more to make St. Clare Commons a true Continuing Care Retirement Community or “Lifetime Campus.”


If you would like more information about St. Clare Commons, please call 419-250-5227, email info(at)stclarecommons(dot)org, click on StClareCommons.org or visit Faceboook.com/StClareCommons for the most up to date news.


REVERENCE        SERVICE        STEWARDSHIP


St. Clare Commons is a member of Franciscan Living Communities and is sponsored by the Sisters of St. Francis of Sylvania, Ohio, in partnership with Blessed John XXIII Catholic Community and the Toledo Diocese. Franciscan Living Communities is a non-profit leading provider of senior living services to 1,200 residents in communities throughout Ohio and Kentucky offering continuing care, independent living, assisted living, rehabilitation, skilled nursing, memory care and adult services. In all relationships, we commit to Reverence for, Service to, and Stewardship of the whole person with whom we are blessed to work. To learn more about Franciscan Living Communities log on to our website at http://www.flcsylvania.org.


Jessica Derkis
St. Clare Commons
419-250-5227
Email Information


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Apothecarie New York Launches New Obagi Hydrate Moisturizer for All-Day Skin Hydration






The multi-action compound provides speedy relief and rejuvenation, and continues to release active compounds for all-day moisturizing protection from wind, sun and environmental elements. Obagi Hydrate, part of the Obagi Nu-Derm System, rejuvenates and restores skin cells to health and vitality.


Brooklyn, NY (PRWEB) December 19, 2012






Apothecarie New York, a premiere provider of skin care products from around the globe, has announced the addition of the new Obagi Hydrate facial moisturizer from Obagi Medical Products to its line of premium products. The innovative moisturizer utilizes hydromanil technology, a natural moisturizing agent from the tara tree seed that works from the inside to enhance skin flexibility and smoothness.


“Most moisturizers on the market today are occlusive, meaning they’re impenetrable,” said Sandy Kohen, a licensed esthetician at Apothecarie New York. “They basically form a shield or film that is spread onto the skin to slow or prevent moisture evaporation. Obagi Hydrate actually penetrates the skin and works from within, keeping you moisturized all day long.”


The seeds have long been known for their unique properties, making them a highly sought ingredient for beauty and medical products. Obagi Medical Products is a leader in physician dispensed skin health systems and has harnessed the healing and restorative powers of the tara tree for its Obagi Hydrate.


“Our customers and their patients have been asking for a moisturizer for years and we’re happy to be bringing to market a product that is clinically proven to do what it says it will do,” said Al Hummel, CEO at Obagi. “Obagi Hydrate offers both instant and long-lasting hydration and is a great adjunct to any of our other Obagi Systems.”


Obagi Hydrate is part of the Obagi Nu-Derm System, the number one physician-dispensed prescription skincare system in the world. It provides immediate moisturizing, prevents further evaporation of moisture from delicate skin, and addresses the signs of photodamage.


The multi-action compound provides speedy relief and rejuvenation, and continues to release active compounds for all-day moisturizing protection from wind, sun and environmental elements. Obagi Hydrate rejuvenates and restores skin cells to health and vitality.


Users will experience a 92 percent improvement in their skin’s moisture content within two hours and increased moisture retention for a full eight hours. Obagi Hydrate has been clinically proven to provide immediate results, and the formula’s unique composition provides users with a 51 percent reduction in moisture loss for long-lasting effects.


The hypoallergenic serum has been allergy tested and specially formulated to be effective for all ages and skin types. Clinically proven to be non-irritating, it combines tara tree seed with Shea and mango butter, avocado and glycerin for healthy, more youthful looking skin. The non-irritating and non-sensitizing facial formula helps fight dryness without clogging pores and leaves no greasy residue.


Obagi Hydrate is available at Apothecarie New York separately or with the Obagi Nu-Derm system for just $ 45.


The addition of Obagi Hydrate to the offerings at Apothecarie New York provides users with a proven formula from a leader in physician-dispensed skin care systems. The hypoallergenic formula works with all skin types to provide immediate and long-term moisturizing from the inside out for beautiful, healthy and younger looking skin.


ABOUT APOTHECARIE NEW YORK



Apothecarie New York is committed to providing customers with advanced and effective skin care products and treatments, and education about skin care choices for their individual needs. The store provides shoppers with free consultations on beauty issues and the company’s estheticians will handpick the products that best fit the needs of the client to repair, maintain and enhance their skin from head to toe.


Apothecarie New York is an authorized partner of Obagi products and Obagi Nu-Derm systems. Purchasing Obagi products through an authorized medical practice is the only way to ensure that the Obagi product is genuine and fresh.


Max Hauer
Apothecarie New York
718.534.0013 215
Email Information


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Number of new drugs picks up in Europe and U.S.






LONDON (Reuters) – The number of new medicines approved or pending approval is on the rise on both sides of the Atlantic, painting an encouraging picture for the global drugs industry as it emerges from a wave of patent expiries.


European regulators said on Tuesday that they expect an increase in new drug applications to about 54 in 2013. In the United States, a total of 34 new drugs have been approved for sale so far in 2012 – the highest level in eight years.






The sector badly needs a pick-up in productivity as companies try to refill their medicine chests after a wave of patient expiries that have peaked this year, depriving leading U.S. and European drug companies of more than $ 30 billion of revenue.


“It bodes well,” said Standard & Poor’s (S&P) analyst Olaf Toelke, who predicts that strong pipelines will allow most large drugmakers to emerge unscathed from the spike in sales losses.


“It shows that companies are addressing the need to find new drugs to replace those facing patent expiration. They have done their homework and it looks as if the industry will be at least stable in future and not fall off the threatened patent cliff.”


The U.S. Food and Drug Administration (FDA), gatekeeper to the world’s biggest pharmaceuticals market, still has just over a week to add more approvals to this year’s tally – and there are signs that the number will increase further.


Three new products for leukemia, anthrax and Cushing’s disease from Ariad Pharmaceuticals, GlaxoSmithKline and Novartis were approved last Friday alone, and the FDA is scheduled to hand down decisions on a further four drugs before the end of the month.


FEWER GENERICS


A green light for all these would take the 2012 tally of new molecular entities (NMEs) approved by the agency’s Center for Drug Evaluation and Research to 38 – two more than the 2004 total of 36.


The European Medicines Agency painted a different picture of improving productivity by announcing that its work program for the year ahead included a forecast for 54 new drug applications, up from 52 in 2012, 48 in 2011 and 34 in 2010. These figures exclude medicines designated for “orphan”, or rare, diseases.


Significantly, the London-based agency is also expecting a sharp drop in the number of applications from companies to sell generic versions of drugs, to 20 in 2013 from 39 in 2012, given the slowdown in patent expiries next year.


Major U.S. drug companies will lose a total of about $ 21 billion in revenue this year from lucrative medicines coming off patent, while the hit for European businesses is about $ 10 billion, according to S&P.


This year’s expiries have included Sanofi and Bristol-Myers Squibb’s heart drug Plavix and AstraZeneca’s antipsychotic Seroquel.


Winning approval from regulators, however, is only part of the battle for drugmakers.


Investors will also be watching closely to see how the new drugs perform commercially once they reach the market, since securing payment for innovative medicines is an increasingly tough fight – especially in austerity-hit Europe.


An analysis by Deloitte and Thomson Reuters this month found that while new drug approvals were increasing, this was offset by lower expected revenues from many individual products.


(Editing by David Goodman)


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Inherited colon cancer risk tied to certain foods






NEW YORK (Reuters Health) – Among people who have a genetic susceptibility to colon cancer, those whose diets are heavy in junk food have an even higher risk, according to a new study.


“These patients have this very high risk because of this (genetic) mutation they have, but it might be that they could reduce the number of (tumors) by having a more healthy lifestyle,” said Akke Botma, the lead author of the study.






Botma’s study is just the first to find a link between certain foods and a higher colon cancer risk in this group, and it can’t prove that the diet is to blame.


All of the people in the study had Lynch syndrome, a genetic disorder that predisposes people to cancer at younger ages and that affects up to one in 660 people.


In Western countries, colorectal and endometrial cancers are the dominant cancers to turn up in people with the syndrome, while in Asia it’s mostly stomach cancer, Botma said.


Up to 70 percent of people with Lynch syndrome will develop colon cancer. Among people without Lynch syndrome, such cancers are thought to be influenced by diet, particularly alcohol and red and processed meat, the authors note in their study, published in the journal Cancer.


Botma and her colleagues at Wageningen University in the Netherlands contacted 486 people with Lynch syndrome from a national database of families with inherited risks for cancer.


At the beginning of the study they surveyed the participants about what they ate, and they ranked each person on whether he ate low, medium or high amounts of foods within four dietary categories.


The food groups included one that was dominated by fruits, vegetables and whole grains; another that was high in meat and coffee; a third dietary group that resembled a Mediterranean diet – fish, leafy greens, pasta, sauces and wine; and a fourth group that was heavy on fried snacks, fast food and diet soda.


Botma and her colleagues found that, over 20 months of follow up, 56 of the participants — or 12 percent — screened positive for tumors in the colon, a precursor to cancer.


Of the four dietary groupings, only the junk food category showed any link with a different risk for developing colon tumors.


Of the 160 people who scored low on the junk food diet, 17 developed tumors, while 18 out of the 160 people who ate the most junk food developed tumors.


The numbers initially seemed similar, but after taking into account smoking and other risk factors, the researchers determined that those in the high junk food group were twice as likely to develop colon tumors.


HOW TO MANAGE RISKS?


“It’s hard to say why” junk food is linked with a greater risk for these tumors, said Dr. Mala Pande, an instructor at the University of Texas MD Anderson Cancer Center in Houston who was not involved in the research.


She said some researchers have suggested that high fat might have something to do with it, but it’s impossible to conclude that from this study.


Although the findings are too preliminary to be used in making dietary recommendations to people with Lynch Syndrome, the study was valuable in launching research into the possible role of certain foods on cancer risk, said Christopher Amos, a professor at the Geisel School of Medicine at Dartmouth College.


“People with Lynch Syndrome are at higher risk, and we’d really like to know how to manage their risks better,” Amos, who was not part of the study, told Reuters Health.


Certain foods have been shown to be linked with different types of cancer, but many of those studies contradict each other and sow confusion (see Reuters Health report of December 5, 2012 here: http://reut.rs/YPuDcs).


Amos said the new study is a good start, but “it would be nice to confirm (it) with additional findings.”


SOURCE: http://bit.ly/SG85JD Cancer, online December 17, 2012.


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Boehner opens door to tax hikes, shifts U.S. fiscal cliff talks






WASHINGTON (Reuters) – U.S. House of Representatives Speaker John Boehner‘s offer to accept a tax rate increase for the wealthiest Americans knocks down a key Republican road block to a deal resolving the year-end “fiscal cliff.”


The question now boils down to what President Barack Obama offers in return. Such major questions, still unanswered so close to the end of the year suggest, however, that no spending and tax agreement is imminent.






A source familiar with the Obama-Boehner talks confirmed that Boehner proposed extending low tax rates for everyone who has less than $ 1 million in net annual income, meaning tax rates would rise on all above that line.


Under current law, the 35 percent top tax rate is scheduled to expire on January 1, and would automatically go to 39.6 percent. Boehner’s proposal would allow that rate to rise as scheduled at a threshold of $ 1 million – putting it back to where it was during the Clinton administration.


The White House has not accepted the proposal and the source could not confirm any additional talks were held on Sunday between Obama and Boehner.


With just over two weeks before the fiscal cliff’s $ 600 billion in automatic tax hikes and spending cuts are triggered, threatening a new recession, there is little time to craft a comprehensive deal that will satisfy both Democrats and Republicans.


Until the latest Republican offer, made on Friday, Boehner had insisted on extending all of the Bush era’s lower tax rates, resisting Obama’s demand to let the marginal rates rise on income above $ 250,000. A rising chorus of business executives also had urged Republicans to agree to this.


Some lawmakers and congressional aides had predicted that Republicans, once serious negotiations began, might try to raise the $ 250,000 threshold, say to $ 500,000 or $ 1 million. They also speculated that Republicans, if forced into a tax rate hike on the upper-income groups, might seek a smaller increase, say to around 37 percent.


Although the White House has not accepted Boehner’s gambit, it could push negotiations away from entrenched, ideological positions.


“Boehner has now accepted the premise of higher rates. So now we’re just arguing over details. I think it’s a significant step,” said Greg Valliere, chief political strategist at Potomac Research Group.


A framework deal spelling out tax revenue and spending cut targets to be finalized in the new year could be possible, Valliere said.


“Boehner’s offer to allow tax rates to go up for taxpayers earning over $ 1 million fundamentally transforms fiscal cliff negotiations,” added Sean West, U.S. policy analyst at Eurasia Group, a political risk consultancy.


In a note to clients, West wrote that it signals, significantly, that Boehner ultimately believes a deal to avoid the cliff is still possible.


“The political burden is now shifted back to the president, who must be willing to take on his party in order to get a deal Boehner can ultimately pass. We do not think the president will overreach: Obama will work with Boehner to get to a deal.”


There are still several critical elements to a deal besides a tax rate increase on the wealthy, including Republican demands to cut spending on social programs.


Changes to the expensive Medicare and Medicaid health care programs for the elderly and the poor could be central to any deal, which must also include an increase in the federal debt limit needed by the end of February.


DEMANDS SOCIAL PROGRAM CUTS


Boehner conditioned his tax rate increase offer on Obama’s agreement to cuts in social program spending, often called entitlements.


Many Republican lawmakers want to raise the eligibility age for Medicare to 67 from 65. They also want to link Medicare to the income of recipients, making wealthier retirees pay more for their care.


Currently, Medicare does have some means testing, charging higher premiums for coverage of doctors visits and prescription drugs to individuals earning more than $ 85,000 and married couples earning more than $ 170,000. Only about 5 percent of recipients pay these higher premiums.


Thus far, Obama has offered only about $ 400 billion in 10-year entitlement savings, mostly through small adjustments in reining in health care costs – not fundamental changes such as raising the eligibility age.


And just as Boehner faces opposition in his own party to raising any tax rates, Obama faces opposition to cuts to Medicare, Medicaid and Social Security from Democrats, who pledged in election campaigns they would protect these programs.


A major bloc of congressional Democrats has already signaled they will not accept major cutbacks in Medicare as part of any fiscal cliff deal.


House Minority Leader Nancy Pelosi of California and Maryland Representative Chris Van Hollen of Maryland are among the high ranking Democrats in the House who have come out forcefully in recent days against raising the age for eligibility for Medicare to 67 years of age.


“Given the level of savings that is being talked about from Medicare, you can’t get it all from providers and drug makers,” said Paul Heldman, an analyst at Potomac Research, which tracks Washington policy for investors.


“So opponents of raising the eligibility age have reason to believe beneficiaries will take some sort of hit if a mega-deal is cut,” he said.


If Republicans are not successful in securing entitlement program cuts in exchange for a tax-rate increase on the wealthy, they are adamant about using a debt-limit increase as leverage to overhaul Social Security and Medicare.


The U.S. Treasury expects to reach its $ 16.4 trillion statutory debt cap by year-end, and will exhaust its remaining borrowing capacity around mid-February, risking a potential default.


Louisiana Republican Representative John Fleming, a member of the conservative Tea Party caucus who has never voted to increase the debt ceiling, said he would support a debt limit hike if it were part of a deal to make Medicare and Social Security sustainable.


The pace of activity could pick up the coming week.


House Republicans were told to prepare for a possible weekend session next week, potentially interrupting travel plans for the long Christmas holiday weekend.


House Majority Leader Eric Cantor scheduled “possible legislation related to expiring provisions of law,” a reference to the expiring tax cuts, for the end of the week, portending a weekend session. Cantor has said the House would meet through the Christmas holidays and beyond.


(This story was fixed to correct current top tax rate to 35 percent from 36 percent)


(Additional reporting by Thomas Ferraro, Richard Cowan and Kim Dixon; Editing by Fred Barbash, Todd Eastham and Jackie Frank)


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Clinton sustains concussion; Benghazi testimony postponed






WASHINGTON (Reuters) – Secretary of State Hillary Clinton, who canceled an overseas trip last weekend because of illness, suffered a concussion after fainting due to dehydration, prompting the postponement of her scheduled congressional testimony on the attack on a U.S. mission in Libya, officials said on Saturday.


“While suffering from a stomach virus, Secretary Clinton became dehydrated and fainted, sustaining a concussion,” State Department spokesman Philippe Reines said in a statement.






“She has been recovering at home and will continue to be monitored regularly by her doctors,” Reines said, adding that she would work from home and stay in regular contact with other top officials.


Clinton, 65, fell ill with a stomach virus last weekend and was forced to cancel a planned trip to the Middle East and North Africa. The virus also hit other members of her staff, who were returning with her from a European trip, and was described as uncomfortable, but not medically serious.


Clinton’s doctors, Lisa Bardack of the Mt. Kisco Medical Group and Gigi El-Bayoumi of George Washington University, issued a statement saying that Clinton fainted as a result of “extreme dehydration” due to the virus.


“Over the course of this week we evaluated her and ultimately determined she had also sustained a concussion,” the doctors said in their statement, which was distributed by the State Department.


“We recommended that the secretary continue to rest and avoid any strenuous activity, and strongly advised her to cancel all work events for the coming week. We will continue to monitor her progress as she makes a full recovery.”


Clinton has often been cited as a potential Democratic candidate for the U.S. presidency in 2016 and frequently refers to her general good health. She said in an interview with ABC broadcast on Wednesday that she has “incredible stamina and energy.”


She has maintained a punishing schedule in her final weeks as the top U.S. diplomat, a position she intends to leave toward the end of January when U.S. President Barack Obama is sworn in for a second term.


Obama telephoned Clinton to wish her well, White House spokesman Tommy Vietor said.


BENGHAZI TESTIMONY NEXT WEEK


Clinton had been expected to testify on December 20 before the House of Representatives and Senate foreign affairs committees on a report on the deadly attack on the U.S. diplomatic post in Benghazi, Libya, in September that killed the U.S. ambassador and three other Americans and raised questions about security at far-flung posts.


Jodi Seth, a spokeswoman for Senate Foreign Relations Committee head John Kerry, said that given her condition, Clinton’s testimony would be postponed, but did not say until when. Seth said the planned hearings would be held with other senior officials appearing in Clinton’s place.


The Republican chair of the House of Representatives Foreign Affairs Committee, Ileana Ros-Lehtinen, issued a statement saying she was sorry to hear of Clinton’s ill health, but it was “unfortunate” she would be unable to testify before the committee next week.


“We still don’t have information from the Obama Administration on what went so tragically wrong in Benghazi that resulted in the deaths of four patriotic Americans,” Ros-Lehtinen said.


“We have been combing through classified and unclassified documents and have tough questions about State Department threat assessments and decision-making on Benghazi. This requires a public appearance by the Secretary of State herself.”


Ros-Lehtinen’s statement said William Burns and Thomas Nides, deputy secretaries of state, would provide testimony in Clinton’s place.


REPUBLICAN CRITICISM


Republicans have criticized the Democratic Obama administration for its early public explanations of the attack.


Much of the criticism focused on U.S. Ambassador to the United Nations Susan Rice, who on Thursday said she was withdrawing her name from consideration to replace Clinton as secretary of state to avoid a potentially disruptive confirmation process.


Clinton has appointed a special panel known as an accountability review board to assess both the Benghazi incident and the official response to it.


The board’s report, which will contain both classified and unclassified sections, is expected to be complete next week and Clinton has promised to be as transparent as possible with Congress in sharing its findings.


Clinton, whose husband, Bill Clinton, was president from 1993 to 2001 and who herself came tantalizingly close to winning the Democratic presidential nomination four years ago, has used her star power to promote U.S. interests around the world since Obama named her to lead the State Department in 2009.


She has consistently been rated as the most popular member of Obama’s Cabinet, leading to speculation she might mount another White House bid in 2016, although she herself has played down suggestions that she still hopes to become president.


“I’ve said I really don’t believe that that’s something I will do again. I am so grateful I had the experience of doing it before,” Clinton told ABC’s Barbara Walters in the interview broadcast on Wednesday.


“I just want to see what else is out there. I’ve been doing … this incredibly important and … satisfying work here in Washington, as I say, for 20 years. I want to get out and spend some time looking at what else I can do to contribute.”


(Reporting by Andrew Quinn and Lisa Lambert; Editing by Will Dunham, David Brunnstrom and Mohammad Zargham)


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Lundbeck’s alcohol dependency drug wins EU green light






LONDON (Reuters) – A novel drug to fight alcohol dependency was given a green light by European regulators on Friday, providing a boost to Danish drugmaker Lundbeck at a time when its top product faces a big drop in sales.


The European Medicines Agency (EMA) said on Friday it recommended approval of Selincro in conjunction with counseling for the reduction of alcohol consumption in adults dependent on drink.






Recommendations from the EMA are normally endorsed by the European Commission within two or three months, implying the drug could be launched in Europe early next year.


That is good news for Lundbeck, which needs new drugs to replace lost sales from antidepressant Cipralex, sold as Lexapro in the United States and Japan, which is now coming off patent.


Alcohol abuse is theoretically a vast market, although it is unclear whether doctors will be ready to prescribe a drug as a treatment and whether Lundbeck has the marketing muscle to make a big impact.


Lundbeck Chief Executive Ulf Wiinberg told Reuters last week that Selincro was “a bit of a joker in our portfolio” because of uncertainty as to how it will be used in practice.


The drug, which blocks the action of opioid receptors in the brain, was licensed to Lundbeck from Finland’s Biotie Therapies and shares in Biotie jumped as much as 16 percent on the news, while Lundbeck rose around 1 percent.


“Clearly, the news is a much-needed boost to sentiment for the (Lundbeck) shares,” said Deutsche Bank analyst Tim Race.


“However, we suspect the market will refrain from pricing-in significant upside from the drug given uncertainties in reimbursement and Lundbeck’s ability to penetrate this market without a major partner.”


Race said current consensus forecasts suggested modest sales of 540 million Danish crowns ($ 95 million) in 2016.


More important for Lundbeck will be the verdict from regulators in North America and Europe late next year on a new antidepressant being developed with Japanese partner Takeda Pharmaceutical that analysts see as a potential $ 1-2 billion-a-year seller.


Developing new treatments for depression has proved an uphill battle for drugmakers in recent times but vortioxetine has produced encouraging clinical trial results and its unique mode of action and flexible dosing could make it a winner.


Another approval prospect for next year is Abilify Maintena, a once-monthly version of schizophrenia drug Abilify that Lundbeck is working on with Otsuka.


Further out, Lundbeck is also developing a drug for the symptoms of Alzheimer’s that will be ready to go into final-stage clinical testing next year and could be partnered with a larger drug company.


(Reporting by Ben Hirschler; Editing by Chris Wickham and Mark Potter)


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Mental health scars common after cardiac arrest






NEW YORK (Reuters Health) – A quarter of cardiac arrest survivors suffer long-term psychological problems such as anxiety, post-traumatic stress disorder and depression, a new review of research estimates.


This additional stress on recovering patients is under-diagnosed, researchers say, and doctors have few standard methods for identifying who is at risk.






“Anxiety, depression and PTSD are major concerns after cardiac arrest,” said lead author Kathryn Wilder Schaaf, a postdoctoral fellow at Virginia Commonwealth University. “We have the tools to treat this, (so) it’s important to make sure that it’s identified,” she added.


Many long-term care issues for survivors are unknown, experts said, largely because only 10 percent of the 382,800 Americans who suffer cardiac arrest each year survive.


And that rate is higher than in the past. Cardiac arrest – when the heart stops beating suddenly and completely – is distinct from conditions often labeled as “heart attacks.” In cardiac arrest, if the heart is not re-started quickly, brain damage or death usually results.


Cold therapy, which can protect the brain for a time, and implanted defibrillator devices, which can re-start an arrested heart, have helped to lower the death toll from cardiac arrest, but little is known about what mental and emotional scars may linger among survivors.


Wilder Schaaf and colleagues reviewed 11 studies published between 1993 and 2011 that looked at mental health issues following cardiac arrests experienced outside of a hospital and found problems plaguing anywhere from 15 percent to 50 percent or more of patients.


Months to years after surviving cardiac arrest, about one-third of patients were depressed and nearly two-thirds were experiencing anxiety. Even PTSD symptoms were surprisingly common, afflicting 19 percent to 27 percent of survivors, the medical literature showed.


In reality, however, the long-term mental health state of many cardiac arrest survivors is not typically considered or assessed, the researchers write in their report, which appears in the journal Resuscitation.


But treating mental illnesses in other types of heart patients has been shown to increase long-term survival while decreasing costs, according to independent research.


In a study published in November, for example, researchers found that a depressed patient recovering from a heart attack treated with psychotherapy and antidepressants during a six-month trial incurred – on average – $ 1,857 in medical costs, whereas a depressed patient who received no psychological treatments cost an average of $ 2,797 over the same time period.


Other research suggests that mental health issues impact physical recovery, too. Over a five-year period, survivors of cardiac arrest and similar events who did not show signs of PTSD lived three and a half times longer than those with ongoing trauma, according to a 2008 study by Dr. Karl-Heinz Ladwig, an epidemiologist at the Helmholtz Zentrum München in Germany.


Stress can affect the nervous system and impact heart rates, as well as worsening chronic inflammation, which also hurts the heart Ladwig told Reuters Health.


“We have problems convincing cardiologists to understand that depression is a very relevant part of their clinical work,” Ladwig said.


Ladwig suggested that doctors can gauge trauma through screening questions that are, “easy to put in a normal discussion.”


“This is a brand new area that is going to require thoughtful scientists, vigilant family members and an awareness from patients,” said Dr. Karina Davidson, director of the Center for Behavioral Cardiovascular Health at Columbia University Medical Center in New York, who was not involved in the new study.


Nightmares plus an avoidance of doctors, medications or follow-up appointments are all signs that a recovering heart patient should seek mental health help, Davidson said.


Psychological recovery includes the patient developing feelings of safety and believing the future will be prosperous, said Samuel Sears, a professor at East Carolina University who studies the psychological effects of cardiac trauma.


A range of tools can help patients achieve that goal, including peer support groups such as the Sudden Cardiac Arrest Survivors Association and smart-phone apps such as ICD Coach (in which Sears has a financial interest), he noted.


Sears said he is optimistic that an understanding of the connection between head and heart will eventually reach the doctor’s office.


SOURCE: http://bit.ly/TUsLLI Resuscitation, online December 3, 2012.


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Thousands trapped, wounded, in Syria’s Deir al-Zor region: MSF






BEIRUT (Reuters) – Fighting has trapped tens of thousands of Syrians in the city of Deir al-Zor and there is urgent need for medical teams to be authorized to evacuate wounded people, Medecins Sans Frontieres (MSF) said on Wednesday.


The group, also known as Doctors Without Borders, said the Syrian government had yet to authorize the deployment of international aid agencies despite the growing humanitarian crisis in the major Arab country, but it would continue to try to raise its presence in Syria to help the wounded.






Deir al-Zor has become one of many urban battlegrounds in the 20-month-old revolt against President Bashar al-Assad in which more than 40,000 have died. With daily army shelling and routes cut off by fighting, many residents are trapped.


“MSF appeals for international and impartial medical assistance to be officially authorized by the government and for such assistance to be respected by all parties of the conflict,” the group said in a statement.


Medical supplies are running short and only a small team of Syrian medics are left inside the embattled eastern city, MSF coordinator Patrick Wieland said, and six months of conflict in Deir al-Zor has left doctors exhausted.


Wieland, who visited the area, said there was now only one makeshift hospital with four doctors in city, which sits near the Iraqi border and was once home to around 600,000 people.


An MSF team unofficially visited Deir al-Zor province but said conditions were too dangerous for them to enter the main city with the same name. The team visited public and private hospitals around the city and said the premises were inundated with wounded, some of them with hundreds of patients.


“Despite support from a Syrian doctors’ organization, medical supplies are almost impossible to get hold of, and aerial bombardments and sniper fire make evacuating patients by stretcher extremely difficult,” the MSF report said.


“The health system is being targeted, and medical supplies, including drugs and blood products, are running out, while the number of wounded continues to increase.”


Other wounded patients, it said, were sent on a 400 km (250 mile) journey to Turkey, even though Deir al-Zor is very close to the Iraqi border, because Turkey has opened up its health care system to wounded Syrians.


“MSF calls for the evacuation of the wounded and sick from the city of Deir al-Zor to safer locations in respect of humanitarian law,” the group said.


(Reporting by Erika Solomon; Editing by Mark Heinrich)


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